protein 1,510 words KG: CASPASE3
Contents

Caspase-3 (CASP3)

🔬 Protein Info
Gene SymbolCASP3
Full NameCaspase-3 (CASP3)
AliasesCASPASE3
Chromosome4q35.1.
Protein FamilyCysteine-aspartate protease (caspase) family
Protein TypeProtein
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionCytoplasm, mitochondria (activated)
Molecular Weight32 kDa (zymogen); 17 + 12 kDa (active heterodimer)
PathwaysApoptosis
UniProt IDP42574
GeneCardsCASP3
Human Protein AtlasCASP3
Associated DiseasesLymphoma
InteractionsAGING, AKT, AKT1, ALZHEIMER, ALZHEIMER'S DISEASE, AND
KG Connections220 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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CASP3 encodes CASPASE3
EHMT2 associated_with CASPASE3
CASPASE3 associated_with BAX
CASPASE3 inhibits JUN
CASPASE3 associated_with CASPASE8
CASPASE3 associated_with BCL2
CASPASE3 associated_with FOXO1
CASPASE8 associated_with CASPASE3
BAX associated_with CASPASE3
JUN inhibits CASPASE3

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