protein 1,089 words KG: CACNA1C
Contents

Cav1.2 - Voltage-Gated L-Type Calcium Channel (CACNA1C)

🔬 Protein Info
Gene SymbolCACNA1C
AliasesPage for Cav1.2
FunctionCACNA1C encodes the alpha-1C subunit of the L-type voltage-gated calcium channel (Cav1.2), one of the most important calcium channels in neurons and cardiac myocytes
Primary Expressionthe brain, heart, and smooth muscle
Subcellular LocalizationSomatodendritic compartment, dendritic spines, cardiac cells
Molecular Weight250 kDa
PathwaysWnt signaling, oxidative stress response
UniProt IDQ13936
GeneCardsCACNA1C
Human Protein AtlasCACNA1C
Associated DiseasesAlzheimer, Anxiety, Cancer, Inflammation, Ms, psychiatric disorders
InteractionsAPP, CACNA1A, CACNA1D, CACNA1E, cacna1f, CACNA1F
KG Connections217 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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UniProtWikipedia

Related Hypotheses (1)

Transcranial Magnetic Stimulation-Induced Nanoparticle Deliv
Score: 0.38

Knowledge Graph (12 edges)

PIEZO1 expressed_in CACNA1C
KCNK2 associated_with CACNA1C
SCN5A associated_with CACNA1C
TRPM7 associated_with CACNA1C
SCN1A associated_with CACNA1C
TRPV4 expressed_in CACNA1C
CACNA1B associated_with CACNA1C
SCNN1A associated_with CACNA1C
CFTR associated_with CACNA1C
PIEZO2 associated_with CACNA1C

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