biomarker 1,103 words KG: NFH
Contents

Neurofilament Heavy Chain (NfH)

🔬 Protein Info
Gene SymbolNFH
Chromosome22q12.2
Functionis a neuronal intermediate filament protein encoded by the NEFH gene on chromosome 22q12.
Molecular Weight200 kDa
Amino Acids816 aa
Exons4
GeneCardsNFH
Human Protein AtlasNFH
NF-L (Light)~61 kDa
NF-M (Medium)~102 kDa
NF-H (Heavy)~200 kDa
Associated Diseasesneurodegeneration
KG Connections14 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (2)

Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.78
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (2)

Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

Related Experiments (6)

Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Alpha-Synuclein Aggregation Triggers — Sporadic PD Initiatio
clinical · proposed · Score: 0.40
Sporadic ALS Initiation Biology: Deep Phenotyping of At-Risk
clinical · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Microbiome-Gut Barrier Signatures in ALS — Experiment Design
clinical · proposed · Score: 0.40

See Also (13)

Neurodegeneration
disease · KG edge: implicated_in
STAT3 (Redirect)
redirect · KG edge: biomarker_for
AKT1 Gene
gene · KG edge: biomarker_for
BCL2L1 Gene
gene · KG edge: biomarker_for
CASP1 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

BCL2L1 biomarker_for NFH
CASP1 associated_with NFH
NFKBIA associated_with NFH
CASP8 biomarker_for NFH
IL1B associated_with NFH
XIAP biomarker_for NFH
AKT1 biomarker_for NFH
STAT3 biomarker_for NFH
CFLAR associated_with NFH
RIPK1 associated_with NFH

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