Resolve how aged tissue niches differentially preserve or erode TRM function across barrier organs and CNS-adjacent sites. Boundary domains: tissue-immunity, neuroinflammation. Representative papers: The role of the CD8+ T cell compartment in ageing and neurodegenerative disorders.; From Tissue to Transcriptome: A Systematic Review of Multi-Level Evidence for Immune Dysregulation in Atrial Fibrillation.; Visual Genomics Analysis Studio as a Tool to Analyze Multiomic Data.
Landscape Summary: Tissue-resident Memory T Cells Across Aging Niches is a 0.667 priority gap in immunology-aging-memory. It has 0 linked hypotheses with average composite score 0.000. Status: open.
Colonna, Sevlever, et al. (TREM2 biology)
Tissue-resident Memory T Cells Across Aging Niches — INVOKE-2 (completed)
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