gene

VPS33A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about VPS33A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

19Connections

0Hypotheses

0Analyses

13Outgoing

6Incoming

0Experiments

0Debates

Summary

Page for VPS33A Gene

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	VPS33A
Aliases	Vacuolar Protein Sorting 33 Homolog A
Chromosome	12q24.31
Protein Type	Gene
Function	is an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight	57.7 kDa
Amino Acids	552 aa
GeneCards	VPS33A
Human Protein Atlas	VPS33A
Associated Diseases	Als
Interactions	AND, ATP, LC3, LYSOSOME, Ras, STX17
KG Connections	19 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

VPS33A Gene

gene · 890 words

→

VPS33A Protein

protein · 1431 words

→

Pathway Diagram

graph TD
    VPS33A["VPS33A"]
    VPS16["VPS16"]
    VPS33A -->|"binds"| VPS16
    Als{"Als"}
    VPS33A -->|"associated with"| Als
    STX17["STX17"]
    VPS33A -->|"inhibits"| STX17
    UVRAG["UVRAG"]
    VPS33A -->|"interacts with"| UVRAG
    VPS33A -->|"inhibits"| VPS16
    LC3["LC3"]
    VPS33A -->|"inhibits"| LC3
    neurodegeneration["neurodegeneration"]
    VPS33A -->|"implicated in"| neurodegeneration
    UVRAG -->|"interacts with"| VPS33A
    STX17 -->|"inhibits"| VPS33A
    style VPS33A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (13)

Target	Relation	Type	Str
VPS16	associated_with	protein	0.90
Als	associated_with	disease	0.65
UVRAG	interacts_with	gene	0.60
VPS16	inhibits	gene	0.60
LC3	inhibits	gene	0.60
COX15	associated_with	gene	0.60
RPL4	associated_with	gene	0.60
STX17	inhibits	gene	0.60
AND	inhibits	gene	0.60
LYSOSOME	interacts_with	gene	0.60
ATP	activates	gene	0.60
ACSL5	associated_with	gene	0.60
Ras	activates	protein	0.60

Incoming (6)

Source	Relation	Type	Str
UVRAG	interacts_with	gene	0.60
STX17	inhibits	gene	0.60
PPP1R7	associated_with	gene	0.60
ABCB1	associated_with	gene	0.60
PEX3	associated_with	gene	0.60
VPS16	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning VPS33A in their description or question text

No additional research found