concept

SLAMF7

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLAMF7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

26Connections

0Hypotheses

0Analyses

18Outgoing

8Incoming

0Experiments

0Debates

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💡 Concept Info

Name	SLAMF7
Key Genes/Proteins	ATF2, BCL-2, CCL2, CCR2, CD38, CTSB
Related Diseases	cancer, Inflammation, Inflammatory Bowel Disease
Related Pathways	cell proliferation, Gut Microbiome

Pathway Diagram

graph TD
    SLAMF7[SLAMF7]
    SLAMF7 -.protects against.-> ovarian_cancer[ovarian cancer]
    SLAMF7 -->|activates| CTSB[CTSB]
    SLAMF7 -->|activates| LAMP1[LAMP1]
    SLAMF7 -->|inhibits| CTSD[CTSD]
    SLAMF7 -->|inhibits| cell_proliferation[cell proliferation]
    SLAMF7 -->|regulates| Inflammatory_Bowel_Disease[Inflammatory Bowel Disease]
    SLAMF7 -.protects against.-> Inflammation[Inflammation]
    SLAMF7 -->|target for| CD38[CD38]
    SLAMF7 -->|activates| TRAF6[TRAF6]
    SLAMF7 -->|activates| cancer[cancer]
    ATF2[ATF2] -->|inhibits| SLAMF7
    CCR2[CCR2] -->|inhibits| SLAMF7
    INFLAMMATION[INFLAMMATION] -.protects against.-> SLAMF7
    CCL2[CCL2] -->|inhibits| SLAMF7
    MAPK[MAPK] -->|inhibits| SLAMF7
    benchmark_ot_ad_answer_key_SLA[benchmark_ot_ad_answer_key:SLAMF7] -->|data_in| SLAMF7

Outgoing (18)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:SLAMF7	data_in	dataset_row	0.00
cell proliferation	inhibits	pathway	0.80
ovarian cancer	protects_against	disease	0.80
CTSB	activates	protein	0.80
LAMP1	activates	protein	0.80
CTSD	inhibits	protein	0.80
Inflammatory Bowel Disease	regulates	disease	0.65
Inflammation	protects_against	disease	0.65
Microbiota	implicated_in	pathway	0.60
Gut Microbiome	regulates	pathway	0.60
BCL-2	therapeutic_target	gene	0.60
CD38	therapeutic_target	gene	0.60
TRAF6	activates	gene	0.60
cancer	activates	disease	0.60
MAPK signaling	participates_in	pathway	0.60
ubiquitin-proteasome	participates_in	pathway	0.60
oxidative stress response	participates_in	pathway	0.60
macrophages	expressed_in	cell_type	0.55

Incoming (8)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:SLAMF7	data_in	dataset_row	0.00
CCR2	inhibits	gene	0.60
CCL2	inhibits	gene	0.60
MAPK	inhibits	gene	0.60
CCL2	activates	gene	0.60
MAPK	activates	gene	0.60
ATF2	inhibits	gene	0.60
INFLAMMATION	protects_against	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SLAMF7 in their description or question text

No additional research found