concept

MURF1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MURF1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

33Connections

0Hypotheses

0Analyses

19Outgoing

14Incoming

0Experiments

0Debates

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💡 Concept Info

Name	MURF1
Key Genes/Proteins	AGING, AKT, AND, GAL, MITOCHONDRIAL DYSFUNCTION, MTOR
Related Diseases	Aging, Als, ALS, Ms
Related Pathways	Akt, Mitochondrial Function, Mtor, Oxidative Stress

Wiki Pages (1)

Knowledge base pages for this entity

SMURF1 Protein

protein · 573 words

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Pathway Diagram

graph TD
    MURF1["MURF1"]
    MURF1 -->|"contributes to"| Skeletal_Muscle_Aging["Skeletal Muscle Aging"]
    MURF1 -->|"activates"| Ms["Ms"]
    MURF1 -->|"activates"| Als["Als"]
    MURF1 -->|"activates"| Aging["Aging"]
    MURF1 -->|"activates"| ALS["ALS"]
    MURF1 -->|"activates"| Akt["Akt"]
    MURF1 -->|"activates"| Pi3K["Pi3K"]
    MURF1 -->|"activates"| Oxidative_Stress["Oxidative Stress"]
    OXIDATIVE_STRESS["OXIDATIVE STRESS"] -->|"activates"| MURF1
    AGING["AGING"] -->|"activates"| MURF1
    AKT["AKT"] -->|"activates"| MURF1
    P21["P21"] -->|"regulates"| MURF1
    P53["P53"] -->|"regulates"| MURF1
    PI3K["PI3K"] -->|"activates"| MURF1
    P16["P16"] -->|"regulates"| MURF1
    PSP["PSP"] -->|"regulates"| MURF1

Outgoing (19)

Target	Relation	Type	Str
Skeletal Muscle Aging	associated_with	process	0.80
ALS	activates	disease	0.65
Ms	activates	disease	0.65
Als	activates	disease	0.65
Aging	activates	disease	0.65
Akt	activates	pathway	0.60
Pi3K	activates	pathway	0.60
Oxidative Stress	activates	pathway	0.60
Mitochondrial Function	activates	pathway	0.60
Mtor	activates	pathway	0.60
PI3K	activates	gene	0.60
PSP	regulates	gene	0.60
ROS	activates	gene	0.60
P16	regulates	gene	0.60
P53	regulates	gene	0.60
P21	regulates	gene	0.60
AGING	activates	gene	0.60
MYOD	regulates	gene	0.60
Pi3K/Akt	activates	pathway	0.60

Incoming (14)

Source	Relation	Type	Str
OXIDATIVE STRESS	activates	gene	0.60
AGING	activates	gene	0.60
AKT	activates	gene	0.60
P21	regulates	gene	0.60
P53	regulates	gene	0.60
PI3K	activates	gene	0.60
P16	regulates	gene	0.60
PSP	regulates	gene	0.60
ROS	activates	gene	0.60
AND	regulates	gene	0.60
MTOR	activates	gene	0.60
GAL	activates	gene	0.60
MYOD	regulates	gene	0.60
MITOCHONDRIAL DYSFUNCTION	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MURF1 in their description or question text

No additional research found