Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MID51: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
MID51 is a gene implicated in neurodegeneration research. Key relationships include: associated with, interacts with, regulates. Associated with Aging, Als, Parkinson. Connected to 26 entities in the SciDEX knowledge graph.
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| Gene Symbol | MID51 |
| Full Name | Mitochondrial Dynamics Protein 51 |
| Chromosome | 22q13.31 |
| Function | MID51 is a key regulator of mitochondrial dynamics |
| UniProt ID | Q9NQC3 |
| NCBI Gene ID | 54471 |
| Ensembl ID | ENSG00000103184 |
| GeneCards | MID51 |
| Human Protein Atlas | MID51 |
| Associated Diseases | Als, Parkinson |
| Interactions | AND, DRP1, MFF, MID49, MIRO1 |
| KG Connections | 29 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
MID51["MID51"]
Aging{"Aging"}
MID51 -->|"regulates"| Aging
Parkinson{"Parkinson"}
MID51 -->|"associated with"| Parkinson
Als{"Als"}
MID51 -->|"associated with"| Als
MID49["MID49"]
MID51 -->|"interacts with"| MID49
MFF["MFF"]
MID51 -->|"interacts with"| MFF
MIRO1["MIRO1"]
MID51 -->|"interacts with"| MIRO1
TOMM20["TOMM20"]
MID51 -->|"regulates"| TOMM20
FIS1["FIS1"]
MID51 -->|"associated with"| FIS1
Mitophagy(["Mitophagy"])
MID51 -->|"associated with"| Mitophagy
NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"]
MID51 -->|"regulates"| NEURODEGENERATIVE_DISEASES
MAX["MAX"]
MID51 -->|"regulates"| MAX
AGING["AGING"]
MID51 -->|"regulates"| AGING
DRP1["DRP1"]
DRP1 -->|"interacts with"| MID51
TOMM20 -->|"regulates"| MID51
MAX -->|"regulates"| MID51
MIRO1 -->|"interacts with"| MID51
MFF -->|"interacts with"| MID51
MID49 -->|"interacts with"| MID51
PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
PARKINSON_S_DISEASE -->|"associated with"| MID51
DRP1 -->|"associated with"| MID51
MITOPHAGY["MITOPHAGY"]
MITOPHAGY -->|"associated with"| MID51
MID49 -->|"associated with"| MID51
MFF -->|"associated with"| MID51
style MID51 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| Aging | regulates | disease | 0.65 |
| Parkinson | associated_with | disease | 0.65 |
| Als | associated_with | disease | 0.65 |
| Mitophagy | associated_with | pathway | 0.60 |
| FIS1 | associated_with | gene | 0.60 |
| MAX | regulates | gene | 0.60 |
| DRP1 | interacts_with | gene | 0.60 |
| NEURODEGENERATIVE DISEASES | regulates | gene | 0.60 |
| AGING | regulates | gene | 0.60 |
| MID49 | interacts_with | gene | 0.60 |
| MFF | interacts_with | gene | 0.60 |
| MIRO1 | interacts_with | gene | 0.60 |
| TOMM20 | regulates | gene | 0.60 |
| MIRO1 | associated_with | entity | 0.60 |
| T Cell | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| AGING | regulates | gene | 0.60 |
| NEURODEGENERATIVE DISEASES | regulates | gene | 0.60 |
| AND | interacts_with | gene | 0.60 |
| MFF | interacts_with | gene | 0.60 |
| PARKINSON'S DISEASE | associated_with | gene | 0.60 |
| MITOPHAGY | associated_with | gene | 0.60 |
| DRP1 | interacts_with | gene | 0.60 |
| TOMM20 | regulates | gene | 0.60 |
| MAX | regulates | gene | 0.60 |
| MIRO1 | interacts_with | gene | 0.60 |
| MID49 | interacts_with | gene | 0.60 |
| DRP1 | associated_with | gene | 0.60 |
| MID49 | associated_with | gene | 0.60 |
| MFF | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MID51 in their description or question text
No additional research found