concept

GLIOBLASTOMA MULTIFORME

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GLIOBLASTOMA MULTIFORME: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

43Connections

0Hypotheses

0Analyses

8Outgoing

35Incoming

0Experiments

0Debates

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💡 Concept Info

Name	GLIOBLASTOMA MULTIFORME

Pathway Diagram

graph TD
    GLIOBLASTOMA_MULTIFORME["GLIOBLASTOMA MULTIFORME"]
    GLIOBLASTOMA_MULTIFORME -->|"causes"| Epilepsy["Epilepsy"]
    cGAS_STING["cGAS-STING"] -->|"targets"| GLIOBLASTOMA_MULTIFORME
    Pi3K["Pi3K"] -->|"upregulates"| GLIOBLASTOMA_MULTIFORME
    AKT["AKT"] -->|"upregulates"| GLIOBLASTOMA_MULTIFORME
    MTOR["MTOR"] -->|"upregulates"| GLIOBLASTOMA_MULTIFORME
    Glycolytic_Flux["Glycolytic Flux"] -->|"upregulates"| GLIOBLASTOMA_MULTIFORME
    SDC1["SDC1"] -.biomarker for.-> GLIOBLASTOMA_MULTIFORME
    Central_Nervous_System["Central Nervous System"] -->|"modulates"| GLIOBLASTOMA_MULTIFORME
    Neuronal_Circuits["Neuronal Circuits"] -->|"interacts"| GLIOBLASTOMA_MULTIFORME

Outgoing (8)

Target	Relation	Type	Str
PI3K/AKT/MTOR Pathway	associated_with	pathway	0.95
Wnt Pathway	associated_with	pathway	0.95
NF-κB Pathway	associated_with	pathway	0.95
TGFB Pathway	associated_with	pathway	0.95
Poor Prognosis	associated_with	phenotype	0.95
Treatment Resistance	associated_with	phenotype	0.90
Epilepsy	causes	disease	0.90
Epilepsy	associated_with	disease	0.90

Incoming (35)

Source	Relation	Type	Str
cGAS-STING	targets	pathway	0.95
Pi3K	upregulates	pathway	0.90
AKT	upregulates	protein	0.90
MTOR	upregulates	protein	0.90
Glycolytic Flux	upregulates	process	0.85
IDH-Wildtype	associated_with	biomarker	0.85
CLDN4	promotes	gene	0.85
Central Nervous System	modulates	process	0.85
Neuronal Circuits	interacts_with	process	0.85
CLDN3	promotes	gene	0.85
SDC1	biomarker_for	protein	0.85
Central Nervous System	regulates	process	0.80
AQP1	involved_in	protein	0.80
Glycolytic Flux Promotion	associated_with	process	0.80
cystamine dihydrochloride	treats	compound	0.75
AQP4	associated_with	protein	0.75
Immunotherapy	treats	process	0.75
autophagy	regulates	process	0.70
SDC1	associated_with	protein	0.70
TGM2	associated_with	protein	0.70
PI3K/AKT/mTOR	regulates	pathway	0.70
Wnt	regulates	pathway	0.70
NF-κB	regulates	pathway	0.70
autophagy	activates	process	0.70
SDC1	biomarker_for	protein	0.70
TGM2	biomarker_for	protein	0.70
TGF-β	regulates	pathway	0.70
PTEN	associated_with	gene	0.70
LOX	biomarker_for	protein	0.70
CLDN1	suppresses	gene	0.70
CLDN5	suppresses	gene	0.70
CLDN3	biomarker_for	gene	0.70
CLDN1	biomarker_for	gene	0.70
Astrocyte-like Neural Stem Cells	involved_in	cell_type	0.70
Outer Radial Glial-like Cells	involved_in	cell_type	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GLIOBLASTOMA MULTIFORME in their description or question text

No additional research found