Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CJD: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| CREUTZFELDT-JAKOB | co_discussed | disease | 0.60 |
| CREUTZFELDT-JAKOB | causes | disease | 0.60 |
| NEURON | causes | cell_type | 0.60 |
| DLB | co_discussed | gene | 0.60 |
| DLB | associated_with | gene | 0.60 |
| STING | co_discussed | gene | 0.60 |
| FRONTOTEMPORAL DEMENTIA | co_discussed | disease | 0.60 |
| FTD | co_discussed | gene | 0.60 |
| LEWY BODY DEMENTIA | co_discussed | disease | 0.60 |
| PARKINSON'S DISEASE | co_discussed | disease | 0.60 |
| CREUTZFELDT-JAKOB | regulates | disease | 0.60 |
| TAU | regulates | gene | 0.60 |
| CREUTZFELDT-JAKOB | expresses | disease | 0.60 |
| OLIGODENDROCYTE | co_discussed | cell_type | 0.60 |
| OLIGODENDROCYTE | associated_with | cell_type | 0.60 |
| TAU | co_discussed | gene | 0.60 |
| PARKINSON | co_discussed | disease | 0.40 |
| PARKINSON'S | co_discussed | disease | 0.40 |
| PARKIN | co_discussed | gene | 0.40 |
| PRION DISEASE | co_discussed | disease | 0.40 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ACHE | treats | gene | 0.65 |
| AD | co_discussed | gene | 0.60 |
| ALZHEIMER'S DISEASE | co_discussed | disease | 0.60 |
| AD | regulates | gene | 0.60 |
| APOPTOSIS | causes | pathway | 0.60 |
| ACHE | co_discussed | gene | 0.60 |
| AD | expresses | gene | 0.60 |
| ALZHEIMER | co_discussed | disease | 0.40 |
| ALZHEIMER'S | co_discussed | disease | 0.40 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| Pre-Symptomatic Detection and Intervention Timing in Genetic Prion Dis | validation | ALS | 0.400 | 0.50 | human | proposed | $2,280,000 |
| Prion Strain Diversity and Selective Vulnerability in CJD | clinical | Neurodegeneration | 0.400 | 0.50 | human | proposed | $5,460,000 |
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CJD in their description or question text
No additional research found