concept

CD39

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CD39: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

28Connections

0Hypotheses

0Analyses

20Outgoing

8Incoming

0Experiments

0Debates

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💡 Concept Info

Name	CD39
Key Genes/Proteins	App, ATP, CX3CR1, DEMENTIA, LRP1, MICROGLIA
Related Diseases	ALS, Dementia, Ischemia

Wiki Pages (1)

Knowledge base pages for this entity

CD39 (ENTPD1) Activators for Neurodegeneration

therapeutic · 1308 words

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Pathway Diagram

graph TD
    CD39["CD39"]
    CD39 -->|"interacts"| A3AR["A3AR"]
    CD39 -->|"interacts"| Ischemia["Ischemia"]
    CD39 -->|"interacts"| Dementia["Dementia"]
    CD39 -->|"interacts"| ALS["ALS"]
    CD39 -->|"interacts"| Vascular_Dementia["Vascular Dementia"]
    CD39 -->|"activates"| ATP["ATP"]
    CD39 -->|"inhibits"| Microglia["Microglia"]
    CD39 -->|"interacts"| RNA["RNA"]
    DEMENTIA["DEMENTIA"] -->|"interacts"| CD39
    OLIGODENDROCYTE["OLIGODENDROCYTE"] -->|"interacts"| CD39
    RNA -->|"interacts"| CD39
    MICROGLIA["MICROGLIA"] -->|"inhibits"| CD39
    AND["AND"] -->|"inhibits"| CD39
    ATP -->|"activates"| CD39

Outgoing (20)

Target	Relation	Type	Str
A3AR	interacts_with	receptor	0.85
Ischemia	interacts_with	disease	0.65
Dementia	interacts_with	disease	0.65
ALS	interacts_with	disease	0.65
Vascular Dementia	interacts_with	disease	0.65
Ras	activates	protein	0.60
App	activates	protein	0.60
RNA	interacts_with	gene	0.60
ATP	activates	gene	0.60
microglia	expressed_in	cell_type	0.60
Microglia	inhibits	cell_type	0.60
P2Y12	activates	gene	0.55
purinergic signaling	participates_in	pathway	0.55
PSP	activates	gene	0.55
Microglia	expressed_in	cell_type	0.55
CX3CR1	activates	gene	0.55
P2X7	activates	gene	0.55
White Matter	expressed_in	brain_region	0.55
Progenitor Cell	expressed_in	cell_type	0.55
Oligodendrocyte	expressed_in	cell_type	0.55

Incoming (8)

Source	Relation	Type	Str
MICROGLIA	inhibits	gene	0.60
ATP	expressed_in	gene	0.60
DEMENTIA	interacts_with	gene	0.60
OLIGODENDROCYTE	interacts_with	gene	0.60
LRP1	associated_with	gene	0.60
SERPINE2	associated_with	gene	0.60
RNA	interacts_with	gene	0.60
ATP	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CD39 in their description or question text

No additional research found