Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TAC3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | TAC3 |
| Key Genes/Proteins | DLK1, DNA, GABRA1, GAIN, GENES, KISS1 |
| Related Diseases | Als, ALS, Central Precocious Puberty |
| Related Pathways | Dna Methylation, Epigenetic, Hypothalamic-Pituitary-Gonadal Axis |
graph TD
TAC3["TAC3"]
TAC3 -->|"involved_in"| Central_Precocious_Puberty_Pro["Central Precocious Puberty Progression"]
TAC3 -->|"involved_in"| Precocious_Puberty["Precocious Puberty"]
TAC3 -->|"involved_in"| Hypothalamic_Pituitary_Gonadal["Hypothalamic-Pituitary-Gonadal Axis"]
TAC3 -->|"contributes to"| Central_Precocious_Puberty["Central Precocious Puberty"]
TAC3 ---|"associated"| ALS["ALS"]
TAC3 ---|"associated"| Als["Als"]
TAC3 ---|"associated"| AND["AND"]
TAC3 ---|"associated"| DLK1["DLK1"]
TAC3 ---|"associated"| KISS1R["KISS1R"]
GENES["GENES"] ---|"associated"| TAC3
LIN28B["LIN28B"] ---|"associated"| TAC3
DNA["DNA"] ---|"associated"| TAC3
GABRA1["GABRA1"] ---|"associated"| TAC3
TACR3["TACR3"] ---|"associated"| TAC3| Target | Relation | Type | Str |
|---|---|---|---|
| Hypothalamic-Pituitary-Gonadal Axis | involved_in | pathway | 0.75 |
| Precocious Puberty | involved_in | disease | 0.75 |
| Central Precocious Puberty Progression | involved_in | process | 0.75 |
| Central Precocious Puberty | contributes_to | disease | 0.70 |
| Central Precocious Puberty | implicated_in | disease | 0.70 |
| Central Precocious Puberty | involved_in | disease | 0.70 |
| Als | associated_with | disease | 0.65 |
| ALS | associated_with | disease | 0.65 |
| Dna Methylation | associated_with | pathway | 0.60 |
| DLK1 | associated_with | gene | 0.60 |
| KISS1R | associated_with | gene | 0.60 |
| Epigenetic | associated_with | pathway | 0.60 |
| MKRN3 | associated_with | gene | 0.60 |
| LIN28B | associated_with | gene | 0.60 |
| TACR3 | associated_with | gene | 0.60 |
| DNA | associated_with | gene | 0.60 |
| GABRA1 | associated_with | gene | 0.60 |
| KISS1 | associated_with | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GENES | associated_with | gene | 0.60 |
| DNA | associated_with | gene | 0.60 |
| TACR3 | associated_with | gene | 0.60 |
| MKRN3 | associated_with | gene | 0.60 |
| GAIN | associated_with | gene | 0.60 |
| KISS1 | associated_with | gene | 0.60 |
| DLK1 | associated_with | gene | 0.60 |
| KISS1R | associated_with | gene | 0.60 |
| GABRA1 | associated_with | gene | 0.60 |
| LIN28B | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning TAC3 in their description or question text
No additional research found