Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about LIN28B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet.
No AI portrait yet
| Name | LIN28B |
| Key Genes/Proteins | AGO2, AND, DLK1, DNA, GABRA1, GAIN |
| Related Diseases | Als, ALS, Central Precocious Puberty |
| Related Pathways | Dna Methylation, Epigenetic |
graph TD
LIN28B["LIN28B"]
LIN28B -->|"involved_in"| Central_Precocious_Puberty_Pro["Central Precocious Puberty Progression"]
LIN28B -->|"involved_in"| Precocious_Puberty["Precocious Puberty"]
LIN28B -->|"contributes to"| Central_Precocious_Puberty["Central Precocious Puberty"]
LIN28B ---|"associated"| ALS["ALS"]
LIN28B ---|"associated"| Als["Als"]
LIN28B ---|"associated"| DNA["DNA"]
LIN28B ---|"associated"| GABRA1["GABRA1"]
LIN28B ---|"associated"| TACR3["TACR3"]
GENES["GENES"] ---|"associated"| LIN28B
TACR3 ---|"associated"| LIN28B
GAIN["GAIN"] ---|"associated"| LIN28B
DNA ---|"associated"| LIN28B
GABRA1 ---|"associated"| LIN28B| Target | Relation | Type | Str |
|---|---|---|---|
| Precocious Puberty | involved_in | disease | 0.75 |
| Central Precocious Puberty Progression | involved_in | process | 0.75 |
| Central Precocious Puberty | implicated_in | disease | 0.70 |
| Central Precocious Puberty | contributes_to | disease | 0.70 |
| Central Precocious Puberty | involved_in | disease | 0.70 |
| ALS | associated_with | disease | 0.65 |
| Als | associated_with | disease | 0.65 |
| DLK1 | associated_with | gene | 0.60 |
| KISS1R | associated_with | gene | 0.60 |
| Epigenetic | associated_with | pathway | 0.60 |
| Dna Methylation | associated_with | pathway | 0.60 |
| TAC3 | associated_with | gene | 0.60 |
| TACR3 | associated_with | gene | 0.60 |
| GABRA1 | associated_with | gene | 0.60 |
| DNA | associated_with | gene | 0.60 |
| MKRN3 | associated_with | gene | 0.60 |
| GAIN | associated_with | gene | 0.60 |
| KISS1 | associated_with | gene | 0.60 |
| AND | associated_with | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GABRA1 | associated_with | gene | 0.60 |
| TACR3 | associated_with | gene | 0.60 |
| GAIN | associated_with | gene | 0.60 |
| DNA | associated_with | gene | 0.60 |
| DLK1 | associated_with | gene | 0.60 |
| MKRN3 | associated_with | gene | 0.60 |
| KISS1R | associated_with | gene | 0.60 |
| TAC3 | associated_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| AGO2 | interacts_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning LIN28B in their description or question text
No additional research found