gene 888 words KG: RCAN1
Contents

RCAN1 Gene

🧬 Gene Info
Gene SymbolRCAN1
Chromosome21q22.12
Protein TypeGene
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionheart and skeletal muscle - RCAN1
Molecular Weight28 kDa
Exons8
PathwaysCBF Pathway
UniProt IDP53805
NCBI Gene ID1077
Ensembl IDENSG00000100097
GeneCardsRCAN1
Human Protein AtlasRCAN1
N-terminal Calcineurin-binding domainMediates interaction with calcineurin
Proline-rich regionsSupport protein-protein interactions
Associated DiseasesALS, disease, Huntington, Huntington's disease, neurodegeneration, oxidative stress
Known Drugs/CompoundsG2-115, memantine
InteractionsACHE, ALZHEIMER, ALZHEIMER'S DISEASE, AMPK, APOPTOSIS,
KG Connections93 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Agent Input

Knowledge Graph (12 edges)

RCAN1 activates TNF
RCAN1 associated_with PI3K
RCAN1 associated_with PP2A
RCAN1 activates ERK1
RCAN1 activates NRF2
RCAN1 activates KEAP1
RCAN1 associated_with AKT
RCAN1 regulates CALCINEURIN
RCAN1 inhibits calcineurin
G2-115 inhibits RCAN1

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