protein 640 words KG: PICK1
Contents

PICK1 Protein

🔬 Protein Info
Gene SymbolPICK1
AliasesPage for PICK1
Chromosome4q24
Protein FamilyPDZ domain proteins
Protein TypeScaffold Protein
FunctionPICK1 (Protein Interacting with C Kinase 1) is a PDZ domain-containing scaffold protein that interacts with protein kinase C (PKC) and various membrane proteins including AMPA receptors, NMDA receptor
Molecular Weight46 kDa
Amino Acids436 aa
UniProt IDQ9NRF5
GeneCardsPICK1
Human Protein AtlasPICK1
Associated Diseasesneurodegeneration
InteractionsAkt, AKT1, CHRNA7, JAK2
KG Connections14 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (8)

NeuRon Therapeutics
company · KG edge: expressed_in
Motor Neuron Disease
redirect · KG edge: interacts_with
Neurodegeneration
disease · KG edge: implicated_in
Neurogenesis
entity · KG edge: interacts_with
AKT1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

PICK1 interacts_with JAK2
PICK1 interacts_with AKT1
PICK1 interacts_with CHRNA7
AKT1 interacts_with PICK1
CHRNA7 interacts_with PICK1
JAK2 interacts_with PICK1
APP regulates PICK1
PICK1 interacts_with Als
PICK1 interacts_with Neurogenesis
PICK1 interacts_with Neuron

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