| Gene Symbol | PICK1 |
| Full Name | Protein Interacting With C Kinase 1 |
| Aliases | Page for PICK1 |
| Protein Family | PDZ domain proteins |
| Protein Type | Scaffold Protein |
| Function | PICK1 (Protein Interacting with C Kinase 1) is a PDZ domain-containing scaffold protein that interacts with protein kinase C (PKC) and various membrane proteins including AMPA receptors, NMDA receptor |
| Molecular Weight | 46 kDa |
| Amino Acids | 436 aa |
| UniProt ID | Q9NRF5 |
| GeneCards | PICK1 |
| Human Protein Atlas | PICK1 |
| Dopamine transporter (DAT) | PICK1 interacts with DAT and influences dopamine reuptake efficiency[^8] |
| GLURδ2/GRID2 | Involved in cerebellar synaptic plasticity[^9] |
| NMDA receptor subunits | Some studies suggest indirect interactions through other scaffolding proteins[^10] |
| Associated Diseases | neurodegeneration |
| Interactions | Akt, AKT1, CHRNA7, JAK2 |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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