| Gene Symbol | MBP |
| Full Name | Myelin Basic Protein |
| Aliases | MBPPROTEIN |
| Chromosome | 18q23 |
| Function | Membrane compaction: MBP interacts with the cytoplasmic surface of the oligodendrocyte membrane, facilitating the tight apposition of myelin lamellae [6] |
| Primary Expression | a developmentally regulated manner, with different isoforms predominant at different stages of oligodendrocyte maturation and myelination |
| Molecular Weight | 21.5 kDa |
| Amino Acids | 197 aa |
| Exons | 11 |
| Pathways | MAPK |
| Ensembl ID | ENSG00000197971 |
| GeneCards | MBP |
| Human Protein Atlas | MBP |
| Primary structure | 144-197 amino acids depending on isoform |
| Post-translational modifications | Multiple phosphorylation sites (Ser, Thr), deimination (citrullination), methylation |
| Associated Diseases | Als, Alzheimer, Alzheimer disease, dementia, Ms |
| Known Drugs/Compounds | metformin |
| Interactions | ACHE, ACSL4, AGING, AKT, ALZHEIMER, ALZHEIMER'S DISEASE |
| SciDEX Hypotheses | Myelin Breakdown-Amyloid Interaction Amplifies Cor |
| KG Connections | 437 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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