protein 737 words KG: ITPR1
Contents

ITPR1 Gene

🔬 Protein Info
Gene SymbolITPR1
Full NameInositol 1,4,5-Trisphosphate Receptor Type 1
AliasesPage for ITPR1
Chromosome3p26.1
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight300 kDa
Amino Acids700 aa
Exons58 exons
PathwaysCalcium Dysregulation
UniProt ID[Q14643](https://www.uniprot.org/uniprot/Q14643)
Ensembl IDENSG00000151952
GeneCardsITPR1
Human Protein AtlasITPR1
Chromosomal location3p26.1
Associated DiseasesDiabetes, stroke
KG Connections30 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

UniProtWikipedia

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (5)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
Genes
index · KG edge: expressed_in
EIF2AK3 - Eukaryotic Translation Initiation Factor 2 Al
gene · KG edge: associated_with
FOXO3 Gene
gene · KG edge: associated_with
GABARAPL2 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

IL12B expressed_in ITPR1
ITPR1 expressed_in MAP1LC3B
ITPR1 expressed_in TIMP1
RAB7A associated_with ITPR1
GABARAPL2 associated_with ITPR1
FOXO3 associated_with ITPR1
LAMP2 associated_with ITPR1
RB1CC1 associated_with ITPR1
EIF2AK3 associated_with ITPR1
GAPDH associated_with ITPR1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.