| Gene Symbol | HSPA1A |
| Full Name | Heat Shock Protein Family A (Hsp70) Member 1A/1B |
| Aliases | HSP70PROTEIN |
| Chromosome | 6p21.33 (HSPA1A), 6p21.33 (HSPA1B) |
| Protein Family | Heat shock protein 70 family (HSP70 superfamily) |
| Protein Type | Chaperone |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Cytoplasm, nucleus (stress-induced) |
| Subcellular Localization | </strong></td><td>Cytosol, nucleus, endoplasmic reticulum, mitochondria</td></tr> |
| Molecular Weight | 70 kDa |
| Amino Acids | 640 aa |
| Pathways | Akt, Apoptosis, Chaperone, Complement, Epithelial-Mesenchymal Transition |
| UniProt ID | P0DMV8 |
| OMIM | 140100 |
| GeneCards | HSPA1A |
| Human Protein Atlas | HSPA1A |
| Associated Diseases | Als, Alzheimer, alzheimer_disease, alzheimers, cancer |
| Known Drugs/Compounds | 5S rRNA, 5S Rrna, aducanumab, Arimoclomol, Geranylgeranylacetone, lecanemab |
| Interactions | Actin, ADAM10, AIMP2-DX2, AKT, AKT1, AKT1S1 |
| KG Connections | 1167 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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