protein 2,239 words KG: GRIN2A
Contents

GRIN2A Protein

🔬 Protein Info
Gene SymbolGRIN2A
AliasesNMDA Receptor Subunit 2A
Functionregulation implicated in Alzheimer's
Primary ExpressionPrefrontal Cortex, Cortex, Hippocampus
Subcellular Localizationsynaptic sites
Molecular Weight180 kDa
Amino Acids838 aa
PathwaysNF-κB
GeneCardsGRIN2A
Human Protein AtlasGRIN2A
Associated DiseasesAlzheimer, schizophrenia
Known Drugs/CompoundsGW201
InteractionsActin, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, Amyloid Beta, AND
KG Connections172 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (5)

APOE-Dependent Autophagy Restoration
Score: 0.85
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.67
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Synaptic Vesicle Tau Capture Inhibition
Score: 0.55

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (11)

Apoptosis in Neurodegeneration
entity · KG edge: expressed_in
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activates
Astrocytes
entity · KG edge: activates
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: expressed_in
Genes
index · KG edge: activates

Knowledge Graph (12 edges)

GRIN2A co_discussed SNAP25
GRIN2A activates KCNIP4
GRIN2A co_discussed NCAM2
GRIN2A co_discussed NRXN1
GRIN2A co_discussed RORA
RORB activates GRIN2A
SLC17A7 biomarker_for GRIN2A
SLC17A6 biomarker_for GRIN2A
SLC12A5 biomarker_for GRIN2A
SYN2 biomarker_for GRIN2A

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