protein 1,590 words KG: DJ1
Contents

DJ-1 Protein

🔬 Protein Info
Gene SymbolDJ
Full Name1 Protein
AliasesDJ1
FunctionDj 1 Protein (Park7) is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Subcellular Localization</td><td>Cytosol, nucleus, mitochondria</td></tr>
GeneCardsDJ
Human Protein AtlasDJ
Associated DiseasesInflammation, Neuroinflammation, Parkinson, Parkinson's disease
Known Drugs/Compoundslevodopa
InteractionsAND, ATP13A2, DNAJC6, FBXO7, GBA1, HIF1A
KG Connections113 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

UniProtWikipedia

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (2)

Epigenetic Dysregulation Validation in Parkinson's Disease
clinical · proposed · Score: 0.40
Experiment: Multi-Ethnic PD GWAS
clinical · proposed · Score: 0.40

See Also (7)

Parkinson Basal Ganglia Circuit
circuit · KG edge: contributes_to
NeuRon Therapeutics
company · KG edge: contributes_to
Neuroinflammation PET Imaging in CBS/PSP
diagnostic · KG edge: contributes_to
Parkin (PARK2)
entity · KG edge: causes
Genes
index · KG edge: associated_with

Knowledge Graph (12 edges)

VPS35 associated_with DJ1
LRRK2 associated_with DJ1
PINK1 associated_with DJ1
PARKIN associated_with DJ1
DJ1 associated_with LRRK2
STING activates DJ1
NRF2 activates DJ1
PINK1 causes DJ1
LRRK2 causes DJ1
VPS35 causes DJ1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.