| Gene Symbol | DCTN1 |
| Full Name | Dynactin Subunit 1 (p150^Glued) |
| Aliases | Dynactin subunit p150^Glued |
| Protein Family | Dynactin complex |
| Function | DCTN1 plays critical roles in neuronal function |
| Subcellular Localization | Cytoplasm, neuronal axons, growth cones |
| Molecular Weight | 150 kDa |
| Amino Acids | 238 aa |
| UniProt ID | Q14203 |
| GeneCards | DCTN1 |
| Human Protein Atlas | DCTN1 |
| N-terminal CAP-Gly domain | Binds to microtubules and tubulin dimers |
| Coiled-coil domains | Mediate protein-protein interactions within the dynactin complex |
| Arginine-rich region | Involved in cargo binding |
| PEST sequences | Signal for protein degradation |
| Associated Diseases | ALS, frontotemporal dementia |
| Interactions | Actin, AND, ARF6, ATG, DYNACTIN, Dynein |
| KG Connections | 43 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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