protein 2,656 words KG: DYNACTIN
Contents

Dynactin Protein

🔬 Protein Info
Gene SymbolDYNACTIN
Protein FamilyDynactin family
FunctionDynein alone exhibits relatively short "runs" along microtubule tracks, typically moving only 0.5-1 μm before dissociating [13].
Subcellular Localization</strong></td><td>Cytoplasm, microtubules</td></tr> [@levy2006]
Molecular Weight150 kDa
PathwaysAxonal Transport, Autophagy, Cholesterol
UniProt IDQ14203
GeneCardsDYNACTIN
Human Protein AtlasDYNACTIN
Associated Diseasesneurodegeneration
InteractionsActin, AUTOPHAGY, AXON, DCTN1, Dynein, DYNEIN
KG Connections38 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (6)

Lysosomal Positioning Dynamics Modulation
Score: 0.69
Autophagosome Maturation Checkpoint Control
Score: 0.71
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (7)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (10)

Bipolar Cells in Visual Processing
cell · KG edge: regulates
blarcamesine-axon
clinical_trial · KG edge: interacts_with
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
DCTN1 (Dynactin Subunit 1)
gene · KG edge: activates
DNAJB6 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

DYNACTIN interacts_with DYNEIN
DYNACTIN transports Axonal Transport
DYNEIN interacts_with DYNACTIN
RILP interacts_with DYNACTIN
DYNACTIN activates LDLR
DYNACTIN interacts_with RAB7
DYNACTIN co_discussed DYNEIN
MIRO1 regulates DYNACTIN
DNAJB6 regulates DYNACTIN
DYNACTIN activates DYNEIN

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