protein 1,364 words KG: CATALASEPROTEIN
Contents

Catalase Protein

🔬 Protein Info
Gene SymbolCATALASE
AliasesComprehensive page on Catalase
Function- β-oxidation support: Handles H₂O₂ generated by fatty acid oxidation
Primary ExpressionCortex, Hippocampus
Subcellular Localizationto peroxisomes in astrocytes and neurons, where it serves as a critical componen
Molecular Weight60 kDa
PathwaysAutophagy, Mitophagy, Cell Cycle, Mapk, Apoptosis
GeneCardsCATALASE
Human Protein AtlasCATALASE
Associated Diseasescancer, oxidative stress
Known Drugs/CompoundsNICOTINAMIDE
InteractionsABCD3, ACHE, Actin, AGING, AKT, ALS
KG Connections588 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (9)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.92
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (11)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed

Related Experiments (2)

Peroxisomal Dysfunction Validation in Parkinson's Disease
validation · proposed · Score: 0.40
Peroxisome Dysfunction Validation in Parkinson's Disease
clinical · proposed · Score: 0.40

See Also (15)

Exosomal Biomarkers in Neurodegeneration
biomarker · Pages share 6 hypotheses
Exosomal miR-155 in Neurodegeneration
biomarker · Pages share 6 hypotheses
IL-6 (Interleukin-6) in Neurodegeneration
biomarker · Pages share 6 hypotheses
Liquid Biopsy in Neurodegeneration
biomarker · Pages share 6 hypotheses
Metabolomic Biomarkers in Neurodegeneration
biomarker · Pages share 6 hypotheses

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