| Gene Symbol | BIN1 |
| Full Name | Bridging Integrator 1 (Amphiphysin 2) |
| Chromosome | 2q14.3 |
| Function | Dimerization and membrane curvature sensing/generation |
| Primary Expression | Cerebral cortex, Hippocampus, White matter, Cerebellum |
| Subcellular Localization | ** | Plasma membrane, T-tubules, endocytic vesicles | |
| Molecular Weight | 70 kDa |
| Exons | 20 |
| Pathways | Autophagy, Complement, Endocytosis, proinflammatory activation |
| UniProt ID | O00499 |
| NCBI Gene ID | 274 |
| Ensembl ID | ENSG00000136717 |
| OMIM | 601248 |
| GeneCards | BIN1 |
| Human Protein Atlas | BIN1 |
| Associated Diseases | aging, Als, Alzheimer, Alzheimer's disease |
| Interactions | ABCA7, Actin, AD, ADAM10, ADAMTS4, AGING |
| KG Connections | 998 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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