| Gene Symbol | APH1A, APH1B |
| Full Name | APH1A |
| Aliases | APH1, aph1 |
| Protein Family | APH-1 family (γ-secretase complex) |
| Protein Type | Gene |
| Function | Complex Formation Initiation: APH-1 binds to presenilin in the ER, initiating complex assembly |
| Primary Expression | Endoplasmic reticulum, Golgi apparatus, plasma membrane |
| Molecular Weight | 35 kDa |
| Amino Acids | 346 aa |
| UniProt ID | Q9WVM4 |
| Associated Diseases | Alzheimer's Disease, Frontotemporal Dementia |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, Gamma-Secretase Complex, NCT, NEURON, PSEN |
| KG Connections | 29 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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