concept

OPRL1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about OPRL1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

27Connections

0Hypotheses

0Analyses

22Outgoing

5Incoming

0Experiments

0Debates

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💡 Concept Info

Name	OPRL1
Key Genes/Proteins	CANCER, CPLX3, GBM, GENES, GLIOBLASTOMA, HCRTR1
Related Diseases	Als, ALS, Cancer, Glioblastoma
Related Pathways	Mapk

Pathway Diagram

graph TD
    OPRL1["OPRL1"]
    OPRL1 -->|"expressed in"| Cancer["Cancer"]
    OPRL1 -->|"expressed in"| ALS["ALS"]
    OPRL1 -->|"expressed in"| Glioblastoma["Glioblastoma"]
    OPRL1 -.biomarker for.-> Als["Als"]
    OPRL1 -->|"expressed in"| GBM["GBM"]
    OPRL1 -->|"expressed in"| HCRTR1["HCRTR1"]
    Curcumin["Curcumin"] -->|"downregulates"| OPRL1
    CPLX3["CPLX3"] -.biomarker for.-> OPRL1

Outgoing (22)

Target	Relation	Type	Str
ALS	expressed_in	disease	0.65
Als	biomarker_for	disease	0.65
Cancer	biomarker_for	disease	0.65
Glioblastoma	biomarker_for	disease	0.65
Glioblastoma	expressed_in	disease	0.65
Cancer	expressed_in	disease	0.65
CPLX3	expressed_in	gene	0.60
GLIOBLASTOMA	expressed_in	gene	0.60
CANCER	expressed_in	gene	0.60
Mapk	expressed_in	pathway	0.60
GBM	biomarker_for	gene	0.60
MAPK	biomarker_for	gene	0.60
HCRTR1	biomarker_for	gene	0.60
GLIOBLASTOMA	biomarker_for	gene	0.60
Mapk	biomarker_for	pathway	0.60
GBM	expressed_in	gene	0.60
Igf	expressed_in	protein	0.60
GENES	associated_with	gene	0.60
HCRTR1	expressed_in	gene	0.60
MAPK	expressed_in	gene	0.60
RNA	expressed_in	gene	0.60
LRRTM2	associated_with	gene	0.60

Incoming (5)

Source	Relation	Type	Str
Curcumin	downregulates	chemical	0.80
LRRTM2	associated_with	gene	0.60
CPLX3	biomarker_for	gene	0.60
CPLX3	expressed_in	gene	0.60
LRRTM2	co_expressed_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning OPRL1 in their description or question text

No additional research found