| Gene Symbol | NF2 |
| Full Name | NF2 (Neurofibromin 2 / Merlin) |
| Aliases | Merlin/Schwannomin |
| Chromosome | 22q12.2 |
| Function | NF2 encodes neurofibromin 2, also known as merlin (moesin-ezrin-radixin-like protein) or schwannomin. |
| Primary Expression | High in Schwann cells, meninges, cerebellum (Purkinje cells), neurons |
| Subcellular Localization | and function. Cell-cell contact promotes the open, active conformation |
| Molecular Weight | 66 kDa |
| Amino Acids | 595 aa |
| Pathways | mTOR signaling, mTOR Signaling, mTOR |
| UniProt ID | P35240 |
| NCBI Gene ID | 4780 |
| Ensembl ID | ENSG00000108775 |
| OMIM | 607402 |
| GeneCards | NF2 |
| Human Protein Atlas | NF2 |
| Associated Diseases | Als, Ms, neurofibromatosis type 2, Tumor |
| Interactions | AKT, AND, CANCER, CDH1, EGFR, ERK |
| KG Connections | 119 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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