protein 3,068 words KG: NEPRILYSIN
Contents

Neprilysin (NEP / CD10 / MME)

🔬 Protein Info
Gene SymbolNEPRILYSIN
Chromosome3q25.2.
Protein TypeProtease
Functionis an important component in the neurobiology of neurodegenerative [diseases.
Primary ExpressionMembrane-bound, presynaptic
Subcellular LocalizationMembrane-bound, presynaptic
Amino Acids750 aa
PathwaysAmyloid, Apoptosis, Blood-Brain Barrier, Epigenetic, Neuroinflammatory
GeneCardsNEPRILYSIN
Human Protein AtlasNEPRILYSIN
Associated DiseasesAlzheimer, Alzheimer'S Disease, disease
InteractionsACE2, AHR, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, Amyloid Beta
KG Connections115 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Knowledge Graph (12 edges)

AHR activates NEPRILYSIN
NEPRILYSIN activates APP
APP activates NEPRILYSIN
FNDC5 inhibits NEPRILYSIN
NEPRILYSIN inhibits STAT3
NEPRILYSIN inhibits HDAC6
NT4 activates NEPRILYSIN
BDNF activates NEPRILYSIN
MECP2 activates NEPRILYSIN
NT3 activates NEPRILYSIN

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