concept

LIN28B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LIN28B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

29Connections

0Hypotheses

0Analyses

19Outgoing

10Incoming

0Experiments

0Debates

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💡 Concept Info

Name	LIN28B
Key Genes/Proteins	AGO2, AND, DLK1, DNA, GABRA1, GAIN
Related Diseases	Als, ALS, Central Precocious Puberty
Related Pathways	Dna Methylation, Epigenetic

Pathway Diagram

graph TD
    LIN28B["LIN28B"]
    LIN28B -->|"involved_in"| Central_Precocious_Puberty_Pro["Central Precocious Puberty Progression"]
    LIN28B -->|"involved_in"| Precocious_Puberty["Precocious Puberty"]
    LIN28B -->|"contributes to"| Central_Precocious_Puberty["Central Precocious Puberty"]
    LIN28B ---|"associated"| ALS["ALS"]
    LIN28B ---|"associated"| Als["Als"]
    LIN28B ---|"associated"| DNA["DNA"]
    LIN28B ---|"associated"| GABRA1["GABRA1"]
    LIN28B ---|"associated"| TACR3["TACR3"]
    GENES["GENES"] ---|"associated"| LIN28B
    TACR3 ---|"associated"| LIN28B
    GAIN["GAIN"] ---|"associated"| LIN28B
    DNA ---|"associated"| LIN28B
    GABRA1 ---|"associated"| LIN28B

Outgoing (19)

Target	Relation	Type	Str
Central Precocious Puberty Progression	involved_in	process	0.75
Precocious Puberty	involved_in	disease	0.75
Central Precocious Puberty	implicated_in	disease	0.70
Central Precocious Puberty	contributes_to	disease	0.70
Central Precocious Puberty	involved_in	disease	0.70
Als	associated_with	disease	0.65
ALS	associated_with	disease	0.65
GABRA1	associated_with	gene	0.60
MKRN3	associated_with	gene	0.60
GAIN	associated_with	gene	0.60
KISS1	associated_with	gene	0.60
AND	associated_with	gene	0.60
DLK1	associated_with	gene	0.60
KISS1R	associated_with	gene	0.60
Epigenetic	associated_with	pathway	0.60
Dna Methylation	associated_with	pathway	0.60
DNA	associated_with	gene	0.60
TAC3	associated_with	gene	0.60
TACR3	associated_with	gene	0.60

Incoming (10)

Source	Relation	Type	Str
TAC3	associated_with	gene	0.60
GABRA1	associated_with	gene	0.60
GENES	associated_with	gene	0.60
AGO2	interacts_with	gene	0.60
TACR3	associated_with	gene	0.60
GAIN	associated_with	gene	0.60
DNA	associated_with	gene	0.60
DLK1	associated_with	gene	0.60
MKRN3	associated_with	gene	0.60
KISS1R	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning LIN28B in their description or question text

No additional research found