gene 527 words KG: CD163
Contents

CD163 (Hemoglobin Scavenger Receptor)

🧬 Gene Info
Gene SymbolCD163
Full NameCD163 Molecule (Hemoglobin Scavenger Receptor)
AliasesHemoglobin Scavenger Receptor
Chromosome12p13.31
Protein TypeReceptor
FunctionCD163 (Cluster of Differentiation 163), also known as the Hemoglobin Scavenger Receptor, is a member of the scavenger receptor family.
PathwaysTGF-β
UniProt ID[Q86VB7](https://www.uniprot.org/uniprot/Q86VB7)
Ensembl IDENSG00000177575
GeneCardsCD163
Human Protein AtlasCD163
Extracellular domain9 scavenger receptor cysteine-rich (SRCR) domains
Transmembrane regionSingle pass
Cytoplasmic tailSignaling capabilities
Associated DiseasesAging, ALS, Cancer, Inflammation, Ms, Neuroinflammation
InteractionsAKT, AMPK, AND, APOC1, APOE, App
KG Connections321 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

CD163 biomarker_for MMP9
CD163 associated_with CD14
CD163 associated_with CD68
CD163 biomarker_for MMP2
CD36 activates CD163
NRF2 activates CD163
CX3CR1 activates CD163
TNF activates CD163
CD163 activates CD68
CD68 associated_with CD163

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