| Gene Symbol | WDFY3 |
| Full Name | WD Repeat and FYVE Domain Containing 3 |
| Chromosome | 4q21.23 |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | PI3P-rich autophagosome formation sites |
| Amino Acids | 528 aa |
| UniProt ID | [Q9Y4E5](https://www.uniprot.org/uniprot/Q9Y4E5) |
| Ensembl ID | ENSG00000155636 |
| OMIM | 617010 |
| GeneCards | WDFY3 |
| Human Protein Atlas | WDFY3 |
| Phosphoinositide-Binding Region | Mediates membrane association |
| LC3-Interacting Region (LIR) | Directly interacts with LC3/GABARAP proteins on the autophagosome membrane<sup>[2]</sup> |
| Ubiquitinated protein aggregates | The protein contains ubiquitin-binding domains that recognize ubiquitinated misfolded proteins<sup>[3]</sup> |
| Associated Diseases | Als, Ms |
| Interactions | AND, GABARAP, LC3 |
| KG Connections | 19 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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