gene 629 words KG: TRIM16
Contents

TRIM16 — Tripartite Motif-Containing Protein 16

🧬 Gene Info
Gene SymbolTRIM16
Full NameTripartite Motif-Containing Protein 16
AliasesTripartite Motif-containing 16
Chromosome17p12
FunctionTRIM16 possesses multiple functional domains that mediate its diverse cellular roles:
Amino Acids640 aa
PathwaysAutophagy
UniProt IDQ9Y2H9
NCBI Gene ID10678
Ensembl IDENSG00000131865
OMIM609678
GeneCardsTRIM16
Human Protein AtlasTRIM16
Cargo recognitionBinds to ubiquitinated protein aggregates
Autophagosome formationRecruits autophagy machinery to aggregate-prone proteins
Associated DiseasesAging, Carcinoma, Tumor
InteractionsAPOPTOSIS, GBM, OPTN
KG Connections29 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

Related Hypotheses (2)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (5)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Apoptosis in Neurodegeneration
entity · KG edge: activates
IL6 (Redirect)
redirect · KG edge: implicated_in
STAT3 (Redirect)
redirect · KG edge: implicated_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: regulates
ERK1 (MAPK3) — Extracellular Signal-Regulated Kinase 1
gene · KG edge: implicated_in

Knowledge Graph (12 edges)

ERK1 implicated_in TRIM16
TRIM16 implicated_in ERK2
TRIM16 implicated_in MAPK3
TRIM16 implicated_in STAT3
TRIM16 implicated_in PI3K
TRIM16 implicated_in FGF2
TRIM16 implicated_in IL6
TRIM16 implicated_in MAPK1
OPTN activates TRIM16
GBM activates TRIM16

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...