gene 853 words KG: TGFB3
Contents

TGFB3 Gene

🧬 Gene Info
Gene SymbolTGFB3
Full NameTransforming Growth Factor Beta 3
Chromosome14q13.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
PathwaysTGF-β, TGF-β signaling
UniProt IDP10615
NCBI Gene ID7049
Ensembl IDENSG00000119699
OMIM190230
GeneCardsTGFB3
Human Protein AtlasTGFB3
Neuronal developmentTGFB3 is critical for neural tube formation and neuronal differentiation during development[@stottmann2004]
SynaptogenesisThe cytokine regulates synapse formation and function[@fukuda2010]
NeuroprotectionTGFB3 protects neurons against various cytotoxic insults[@unsicker2013]
Wound healingTGFB3 promotes tissue repair following neural injury[@eltzschig2018]
Associated DiseasesMigraine
KG Connections22 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
CDK4 Gene
gene · KG edge: associated_with
CHD4 Gene
gene · KG edge: associated_with
CSF2 — Colony Stimulating Factor 2 (GM-CSF)
gene · KG edge: expressed_in
EP300 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

KCNK5 associated_with TGFB3
TGFB1 associated_with TGFB3
TP53 associated_with TGFB3
NR1D1 associated_with TGFB3
FXN associated_with TGFB3
EPHA5 associated_with TGFB3
EP300 associated_with TGFB3
NLGN2 associated_with TGFB3
CDK4 associated_with TGFB3
CHD4 associated_with TGFB3

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