| Gene Symbol | TDP1 |
| Full Name | Tyrosyl-DNA Phosphodiesterase 1 |
| Chromosome | 14q32.12 |
| Function | The TDP1 gene encodes Tyrosyl-DNA Phosphodiesterase 1, involved in DNA repair and genomic stability |
| UniProt ID | Q9NZJ8 |
| NCBI Gene ID | 70099 |
| Ensembl ID | ENSG00000124564 |
| OMIM | 605197 |
| GeneCards | TDP1 |
| Human Protein Atlas | TDP1 |
| DNA repair | Critical for maintaining genomic integrity |
| Cell cycle regulation | Coordinates DNA repair with cell cycle progression |
| [Apoptosis](/entities/apoptosis) | Modulates apoptotic response to DNA damage |
| Neuronal survival | Essential for long-term neuronal survival |
| H493R | functional studies |
| Associated Diseases | neurodegeneration |
| Interactions | AND, App, CANCER, DNA, FEN1, HIF1A |
| KG Connections | 43 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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