gene 971 words KG: SV2A
Contents

SV2A — Synaptic Vesicle Protein 2A

🧬 Gene Info
Gene SymbolSV2A
Full NameSynaptic Vesicle Protein 2A
Chromosome1p31.1
Protein TypeTransporter
FunctionSV2A is an integral membrane protein localized to synaptic vesicles
Subcellular Localizationsynaptic vesicles:
PathwaysSynaptic vesicle formation
UniProt IDQ9H0Y5
NCBI Gene ID9902
Ensembl IDENSG00000159166
OMIM158621
GeneCardsSV2A
Human Protein AtlasSV2A
Associated DiseasesALS
InteractionsANXIETY, GAP43, GFAP, Proteins, PSD95, SAPAP3
KG Connections34 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (20)

Microglia-Derived Extracellular Vesicle Engineering for Targ
Score: 0.48
SASP-Mediated Complement Cascade Amplification
Score: 0.91
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.72
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.72

Related Analyses (18)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Experiment Scoring Methodology
clinical · proposed · Score: 0.40

See Also (9)

Synaptophysin - Synaptic Biomarker
biomarker · KG edge: associated_with
Hippocampus
brain · KG edge: expressed_in
Striatum
brain · KG edge: expressed_in
Neurodegeneration
disease · KG edge: implicated_in
GAP43 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

SV2A involved_in neuroplasticity
SV2A associated_with GAP43
SV2A associated_with PSD95
SV2A associated_with SYNAPTOPHYSIN
SV2A expressed_in Amygdala
SV2A expressed_in Striatum
SYNAPTOPHYSIN interacts_with SV2A
GAP43 interacts_with SV2A
PSD95 interacts_with SV2A
SV2A co_expressed_with SYP

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)