concept

SAPAP3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SAPAP3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

27Connections

0Hypotheses

0Analyses

19Outgoing

8Incoming

0Experiments

0Debates

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💡 Concept Info

Name	SAPAP3
Key Genes/Proteins	AND, ANXIETY, GAP43, PSD95
Related Diseases	Als, ALS, Anxiety, obsessive-compulsive disorder, Obsessive-Compulsive Disorder

Pathway Diagram

graph TD
    SAPAP3["SAPAP3"]
    SAPAP3 -->|"expressed in"| Astrocyte["Astrocyte"]
    SAPAP3 -->|"target for"| Anxiety["Anxiety"]
    SAPAP3 -->|"interacts"| PSD95["PSD95"]
    SAPAP3 -->|"target for"| ANXIETY["ANXIETY"]
    SAPAP3 -->|"target for"| Rb["Rb"]
    SAPAP3 -->|"expressed in"| Amygdala["Amygdala"]
    SAPAP3 -->|"expressed in"| Cortex["Cortex"]
    SAPAP3 -->|"expressed in"| Hippocampus["Hippocampus"]
    PSD95 -->|"interacts"| SAPAP3

Outgoing (19)

Target	Relation	Type	Str
Astrocyte	expressed_in	cell_type	0.90
Obsessive-Compulsive Disorder	associated_with	disease	0.80
Als	associated_with	disease	0.65
Anxiety	associated_with	disease	0.65
ALS	associated_with	disease	0.65
Anxiety	therapeutic_target	disease	0.65
striatum	expressed_in	brain_region	0.60
PSD95	interacts_with	protein	0.60
obsessive-compulsive disorder	associated_with	disease	0.60
PSD95	associated_with	gene	0.60
ANXIETY	therapeutic_target	gene	0.60
Rb	therapeutic_target	protein	0.60
SV2A	interacts_with	gene	0.60
amygdala	expressed_in	brain_region	0.60
hippocampus	expressed_in	brain_region	0.60
Hippocampus	expressed_in	brain_region	0.55
Striatum	expressed_in	brain_region	0.55
Cortex	expressed_in	brain_region	0.55
Amygdala	expressed_in	brain_region	0.55

Incoming (8)

Source	Relation	Type	Str
PSD95	interacts_with	gene	0.60
ANXIETY	associated_with	gene	0.60
SV2A	associated_with	gene	0.60
GAP43	associated_with	gene	0.60
PSD95	associated_with	gene	0.60
AND	associated_with	gene	0.60
SYNAPTOPHYSIN	associated_with	gene	0.60
GAP43	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SAPAP3 in their description or question text

No additional research found