| Gene Symbol | STXBP1 |
| Full Name | Syntaxin Binding Protein 1 (Munc18-1) |
| Aliases | MUNC18-1 |
| Protein Type | Protein |
| Function | is a neuronal protein essential for synaptic vesicle release and neurotransmitter secretion. |
| Primary Expression | non-neuronal tissues, important for immune function |
| Subcellular Localization | </th><td>Cytoplasm, Presynaptic Terminal, Synaptic Vesicles</td></tr> |
| Molecular Weight | 66 kDa |
| Amino Acids | 594 aa |
| UniProt ID | Search UniProt |
| GeneCards | STXBP1 |
| Human Protein Atlas | STXBP1 |
| Domain 1 (N-terminal) | Binds to the N-terminal region of syntaxin |
| Domain 2 (central) | Forms a deep groove for syntaxin binding |
| Domain 3 (C-terminal) | Contacts the SNARE complex |
| Associated Diseases | ALS, neurodegeneration |
| Interactions | DNAJC5, ERK, GENES, HSC70, MUNC18-1, NEURODEGENERATION |
| KG Connections | 35 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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