gene 1,474 words KG: CDKL5
Contents

CDKL5 Gene

🧬 Gene Info
Gene SymbolCDKL5
Full NameCyclin-Dependent Kinase-Like 5
ChromosomeXp22.13
Protein FamilyCDK family (CDK1-18), MAPK/CDK group
Protein TypeKinase
Functionencodes a serine-threonine kinase expressed predominantly in the developing brain, particularly in neurons.
Primary ExpressionBrain (neurons, high in cortex, hippocampus, cerebellum); low elsewhere
Molecular Weight145 kDa
Amino Acids075 aa
PathwaysMAPK
UniProt IDQ6VAC4
NCBI Gene ID6792
Ensembl IDENSG00000008086
OMIM300203
GeneCardsCDKL5
Human Protein AtlasCDKL5
Associated Diseasesneurodegeneration
InteractionsAPOPTOSIS, ERK
KG Connections16 knowledge graph edges
DatabasesGeneCardsHPASTRING

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