gene 1,304 words KG: STAT5B
Contents

STAT5B Gene

🧬 Gene Info
Gene SymbolSTAT5B
Full NameSignal Transducer and Activator of Transcription 5B
Chromosome12p13.31
Functionencodes a protein of approximately 787 amino acids.
Amino Acids787 aa
Exons19
PathwaysJAK-STAT, NF-κB
UniProt ID[P51692](https://www.uniprot.org/uniprot/P51692)
Ensembl IDENSG00000173728
GeneCardsSTAT5B
Human Protein AtlasSTAT5B
STAT-binding sitesAutoregulation by STAT5 signaling
NF-κB elementsIntegration with inflammatory signals
Cell-type specific enhancersDirect immune and neuronal expression
TATA boxInitiator-driven transcription
Associated DiseasesCancer
KG Connections25 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

Notch and Gamma-Secretase Modulators for Parkinson's Di
company · KG edge: associated_with
Neurodegeneration
disease · KG edge: implicated_in
mTOR Signaling Dysregulation in Progressive Supranuclea
event · KG edge: associated_with
Complement System Dysregulation in Neurodegeneration -
gap · KG edge: associated_with
CCR8 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

MS4A4A associated_with STAT5B
CCR8 associated_with STAT5B
LAG3 associated_with STAT5B
TGFB1 associated_with STAT5B
FOXP3 associated_with STAT5B
CD163 associated_with STAT5B
STAT5B associated_with Il-6
STAT5B associated_with Stat3
COMPLEMENT associated_with STAT5B
KRAS associated_with STAT5B

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