| Gene Symbol | RPL17 |
| Full Name | Ribosomal Protein L17 |
| Chromosome | 18q21.1 |
| Function | RPL17 encodes Ribosomal Protein L17 (also known as L23), a component of the large (60S) ribosomal subunit. |
| Primary Expression | AD brain [@hernandezortega2016] - RPL17 shows altered expression in AD temporal lobe - Global translation deficits in AD neurons correlate with cognit |
| UniProt ID | P18621 |
| NCBI Gene ID | 6169 |
| GeneCards | RPL17 |
| Human Protein Atlas | RPL17 |
| Protein synthesis | Part of the peptidyl transferase center [@yoshikawa2018] |
| Ribosome assembly | Critical for proper 60S subunit formation |
| rRNA binding | Interacts with 28S rRNA |
| Translation termination | Contributes to release factor recognition |
| Associated Diseases | ankylosing spondylitis, migraine, osteoporosis |
| Interactions | YBX1 |
| KG Connections | 11 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!