| Gene Symbol | SLC31A1 |
| Full Name | Solute Carrier Family 3 Member 1A1 (SLC31A1) |
| Chromosome | 9q32 |
| Function | is an essential trace element required for the activity of numerous enzymes critical to energy metabolism, antioxidant defense, neurotransmitter synthesis, and iron metabolism. |
| Primary Expression | virtually all tissues, with particularly high expression in: |
| Pathways | Akt |
| UniProt ID | O15431 |
| NCBI Gene ID | 10551 |
| Ensembl ID | ENSG00000137767 |
| OMIM | 603085 |
| GeneCards | SLC31A1 |
| Human Protein Atlas | SLC31A1 |
| High affinity | Kd in the low micromolar to nanomolar range |
| Rapid kinetics | Enables efficient copper acquisition even at low extracellular concentrations |
| Regulated expression | CTR1 levels are adjusted based on cellular copper status |
| Associated Diseases | neurodegeneration |
| Interactions | AKT, ATF3, CLOCK, DLAT, HSP70, PER2 |
| KG Connections | 10 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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