| Gene Symbol | POU5F1 |
| Full Name | POU Class 5 Homeobox 1 (OCT4) |
| Chromosome | 6p21.33 |
| Protein Type | Transcription Factor |
| Function | is a key transcription factor that plays a fundamental role in maintaining cellular pluripotency—the ability of a cell to differentiate into any cell type in the body. |
| Molecular Weight | 38.5 kDa |
| Amino Acids | 360 aa |
| Pathways | Pluripotency |
| UniProt ID | Q9U5J1 |
| NCBI Gene ID | 27008 |
| Ensembl ID | ENSG00000212749 |
| GeneCards | POU5F1 |
| Human Protein Atlas | POU5F1 |
| Octamer motif recognition | The canonical "ATTTGCAT" sequence |
| Composite elements | Additional sequences that modify binding |
| Associated Diseases | Cancer, Developmental Disorders, Infertility |
| Interactions | AND, App, DNA, HDAC9, KDR, KLF4 |
| KG Connections | 20 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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