gene 1,127 words KG: PEX14
Contents

PEX14 (Peroxisome Biogenesis Factor 14)

🧬 Gene Info
Gene SymbolPEX14
Full NamePeroxisome Biogenesis Factor 14
Chromosome1p36.22
Protein FamilyPEX proteins, peroxisomal import machinery
Functionencodes a critical component of the peroxisomal import machinery—the docking receptor for matrix proteins entering the peroxisome lumen.
Primary Expressionmost tissues:
Subcellular LocalizationPeroxisomal membrane
Amino Acids377 aa
UniProt IDQ15818
NCBI Gene ID5195
Ensembl IDENSG00000134001
OMIM603714
GeneCardsPEX14
Human Protein AtlasPEX14
Associated DiseasesInflammation, Parkinson
InteractionsLC3, OPTN
KG Connections30 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Lysosomal Positioning Dynamics Modulation
Score: 0.69

Related Analyses (2)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

Parkinson Basal Ganglia Circuit
circuit · KG edge: associated_with
Neurodegeneration
disease · KG edge: implicated_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
Complement System Dysregulation in Neurodegeneration -
gap · KG edge: associated_with
Genes
index · KG edge: associated_with

Knowledge Graph (12 edges)

OPTN interacts_with PEX14
PEX14 regulates LC3
ATF6 associated_with PEX14
BECN1 associated_with PEX14
PEX14 associated_with CXCR4
PEX14 associated_with LAMP1
PEX14 associated_with VEGFA
CXCR4 associated_with PEX14
LAMP1 associated_with PEX14
LAMP1 expressed_in PEX14

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.