gene 647 words KG: PEX1
Contents

PEX1 Gene - Peroxisome Biogenesis Factor 1

🧬 Gene Info
Gene SymbolPEX1
Full NamePeroxisome Biogenesis Factor 1
AliasesPage for PEX1 Gene, Page for PEX1 Protein
Chromosome7q31.2
FunctionPEX1 encodes an ATPase belonging to the AAA (ATPases Associated with diverse cellular Activities) family.
Subcellular LocalizationPeroxisomal matrix
Molecular Weight~144 kDa
UniProt IDP50579
NCBI Gene ID5279
Ensembl IDENSG00000127980
GeneCardsPEX1
Human Protein AtlasPEX1
Encoded ProteinPex1p
Associated Diseasesneurodegeneration
InteractionsCAT, PEX3, YBX1
KG Connections6 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Extracellular Vesicle Biogenesis Modulation
Score: 0.58

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (3)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Peroxisomal Dysfunction Validation in Parkinson's Disease
validation · proposed · Score: 0.40

See Also (8)

Ubiquitin-Proteasome System Therapeutic Companies for P
company · KG edge: regulates
Neurodegeneration
disease · KG edge: implicated_in
Tumor Necrosis Factor (TNF)
entity · KG edge: regulates
CAT — Catalase
gene · KG edge: inhibits
PEX3 Gene - Peroxisome Biogenesis Factor 3
gene · KG edge: inhibits

Knowledge Graph (6 edges)

PEX3 inhibits PEX1
UBIQUITIN regulates PEX1
YBX1 inhibits PEX1
CAT inhibits PEX1
PEX1 regulates Als
PEX1 regulates Tumor

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