| Gene Symbol | NOX4 |
| Full Name | NADPH Oxidase 4 |
| Chromosome | 11q14.3 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | neurons, astrocytes, microglia, and endothelial cells within t |
| Molecular Weight | 67 kDa |
| Amino Acids | 578 aa |
| Pathways | Amyloid, Oxidative Stress |
| UniProt ID | [Q9NPH5](https://www.uniprot.org/uniprot/Q9NPH5) |
| Ensembl ID | ENSG00000188882 |
| OMIM | 605966 |
| GeneCards | NOX4 |
| Human Protein Atlas | NOX4 |
| N-terminal transmembrane domains (6×) | Span the membrane and contain heme-binding sites |
| Dehydrogenase domain | Located in the cytoplasm, contains FAD and NADPH binding sites |
| Associated Diseases | neurodegeneration |
| Known Drugs/Compounds | CLEMASTINE |
| Interactions | AGING, AKT, ALOX12, ALOX15, ALS, AMPK |
| KG Connections | 229 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!