| Gene Symbol | NEIL3 |
| Full Name | Nei-Like DNA Glycosylase 3 |
| Chromosome | 4q34.3 |
| Protein Type | Enzyme |
| Function | encodes a DNA repair enzyme that specializes in removing oxidized purine bases from DNA, particularly in proliferating cells and neural tissue. |
| Primary Expression | stem cells and neural tissue, where it plays crucial roles in maintaining genomic integrity during neurogenesis and other developmental processes |
| Molecular Weight | 60 kDa |
| Amino Acids | 605 aa |
| UniProt ID | Q8TCJ1 |
| NCBI Gene ID | 55247 |
| Ensembl ID | ENSG00000128590 |
| OMIM | 608773 |
| GeneCards | NEIL3 |
| Human Protein Atlas | NEIL3 |
| 8-oxoguanine (8-oxoG) | The most common oxidative DNA lesion |
| Associated Diseases | neurodegeneration |
| Interactions | ABCB1, BRAF, CANCER, ERK, NEIL1, NEIL2 |
| KG Connections | 11 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!