gene 550 words KG: NCL
Contents

NCL — Nucleolin

🧬 Gene Info
Gene SymbolNCL
Full NameNucleolin
Chromosome2q37.1
FunctionNucleolin performs diverse cellular functions
Primary ExpressionNucleolus, Brain (neurons, hippocampus, cortex)
PathwaysMicrorna
UniProt IDP19367
NCBI Gene ID4690
Ensembl IDENSG00000115053
OMIM164035
GeneCardsNCL
Human Protein AtlasNCL
Associated DiseasesALS, Alzheimer's Disease, autoimmune diseases, neurodegeneration, viral infections
InteractionsAIF1, ATP, BECN1, CTSB, CTSD, CTSL
KG Connections72 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

Retinal Vascular Microcirculation Rescue
Score: 0.72
Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.71
Nucleolar Stress Response Normalization
Score: 0.65
Blocking AGE-RAGE Signaling in Enteric Glia to Prevent Neuro
Score: 0.61

Related Analyses (3)

CRISPR-based therapeutic approaches for neurodegenerative di
neurodegeneration · archived
Extracellular vesicle biomarkers for early AD detection
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

Microglial Aging and Immune Memory in Neurodegeneration — Tr
validation · proposed · Score: 0.40
Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40
Mechanism: Progranulin Loss and TDP-43 Pathology in FTD
validation · proposed · Score: 0.40
TDP-43 PET Ligand Development for FTD and ALS
clinical · proposed · Score: 0.40

See Also (7)

Apoptosis in Neurodegeneration
entity · KG edge: involved_in
Genes
index · KG edge: regulates
MST1 Gene
gene · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: therapeutic_target
erk-mapk-signaling-neurodegeneration
mechanism · KG edge: activates

Knowledge Graph (12 edges)

NCL involved_in Chromatin Remodeling
NCL involved_in DNA Recombination
NCL involved_in DNA Replication
NCL regulates RNA Transcription
NCL involved_in rRNA Processing
NCL involved_in mRNA Stabilization
NCL associated_with Viral Infections
NCL associated_with Autoimmune Diseases
NCL upregulates Cell Proliferation
NCL involved_in Cytokinesis

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