| Gene Symbol | MSH6 |
| Full Name | MutS Homolog 6 |
| Aliases | Page for MSH6 Protein |
| Function | MSH6 forms a heterodimer with MSH2 (MutSα): |
| Molecular Weight | 160 kDa |
| Pathways | Apoptosis, Dna Repair, Epigenetic, Mtor |
| Ensembl ID | ENSG00000182162 |
| GeneCards | MSH6 |
| Human Protein Atlas | MSH6 |
| Neuronal DNA repair | Active base excision repair and MMR in post-mitotic neurons |
| Somatic mutation prevention | Prevents accumulation of mutations in long-lived neurons |
| Transcriptional fidelity | Maintains accuracy of gene expression |
| Associated Diseases | Als, Cancer, Colorectal Cancer, Gastric Cancer, glioblastoma |
| Interactions | CDK1, LIG1, MLH1, MSH2, MSH3, PMS2 |
| KG Connections | 71 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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