| Gene Symbol | GNPTAB |
| Full Name | N-Acetylglucosamine-1-Phosphate Transferase Alpha/Beta |
| Chromosome | 12q23.2 |
| Protein Type | Enzyme |
| Function | The 1,456 amino acid precursor protein undergoes autocatalytic cleavage in the endoplasmic reticulum to generate the active alpha (catalytic) and beta subunits. |
| Subcellular Localization | the cis-Golgi network. The 1,456 amino acid precursor protein undergoes autocatalytic cleavage in the endoplasmic reticu |
| Amino Acids | 456 aa |
| Pathways | Alpha-Synuclein, Cholesterol |
| UniProt ID | Q3YQZ3 |
| NCBI Gene ID | 57157 |
| Ensembl ID | ENSG00000164930 |
| OMIM | 607840 |
| GeneCards | GNPTAB |
| Human Protein Atlas | GNPTAB |
| Autophagy | Lysosomal function is essential for autophagic degradation of damaged organelles and protein aggregates |
| Associated Diseases | neurodegeneration |
| Interactions | AGING, ALPHA-SYNUCLEIN, CTSD, GBA, GENES, LIPA |
| KG Connections | 35 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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